Guanidine hydrochloride CAS 50-01-1

Guanidine hydrochloride Quick Details

Chemical Name: Guanidine hydrochloride

Synonyms: Guanidine HCl; Guanidinium chloride; Aminoformamidine hydrochloride

CAS No.: 50-01-1

Molecular Formula: CH6ClN3

Molecular weight: 95.53

Chemical Structure:

Appearance: White crystalline powder

Assay: 99%min

Typical properties

CAS 50-01-1 Usage

• Molecular Biology & Biotechnology (Core Fundamental Application): Serves as the premier chaotropic agent and protein denaturant in genomic extraction and structural biology protocols.

  • RNA/DNA Extraction & Lysis: Formulated as a crucial chaotic salt inside viral/cellular lysis buffers to instantly disrupt cell membranes and irreversibly deactivate endogenous nucleases (RNases/DNases), preserving intact nucleic acid integrity.

  • Protein Unfolding & Inclusion Body Solubilization: Applied to denature and solubilize recombinant protein inclusion bodies, stripping native tertiary structures to enable downstream chromatographic purification and refolding workflows.

• Pharmaceutical Intermediate: Deployed as a key building block in synthesizing pyrimidine-ring APIs, including antiviral agents and antidiabetic therapeutics.

• Agrochemicals & Fine Chemicals: Handled as an organic synthesis precursor for triazole fungicides, flame retardants, textile processing auxiliaries, and specialty surfactants.

Packaging and Shipping

25kg per bag.

CAS 50-01-1 Storage

Highly hygroscopic; rapidly absorbs atmospheric humidity to cake and exert mild metallic corrosion.

Must be stored in a cool, dry, and well-ventilated dedicated chemical warehouse.

Keep away from heat sources and open flames; suggested storage temperatures should not exceed 30°C.

Keep containers hermetically sealed and sheltered from ambient humidity.