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Croscarmellose Sodium Cas 74811-65-7

Product name: Croscarmellose Sodium

Appearance: Off-white to white powder

Packing: 200KG/Bag

Sample: Available

Description

CROSCARMELLOSE SODIUM Quick Details

Chemical Name: CROSCARMELLOSE SODIUM

CAS No.: 74811-65-7

Molecular weight: 0

Appearance: Off-white to white powder

Typical Properties

Item Specifications
Description Off-white to white powder
PH 5.0-7.0
Settling volume 10-30ml
Degree of substitution 0.6-0.85%
Sodium chloride and Sodium glycolate ≦0.5%
Content of water-soluble material ≦10%
Loss on drying(%) ≦10%
Residue on ignition 14-28%
Heavy metals ≦10ppm
Total aerobic microbial count ≦1000 CFU/gm
Total mold sand yeasts ≦100 CFU/gm
Escherichia coil Absent

CROSCARMELLOSE SODIUM Usage

As pharmaceutical raw materials, pharmaceutical intermediates.

Croscarmellose Sodium (CAS 74811-65-7) is primarily used as a disintegrant in pharmaceutical formulations, particularly in tablets and capsules. It helps these dosage forms break down rapidly upon contact with moisture, facilitating the release and absorption of the active drug. Additionally, it finds use in the textile and paper industries, as an insecticide, and in oil-well drilling operations.

Here’s a more detailed breakdown:
1. Pharmaceutical Applications:
Disintegrant:
Croscarmellose sodium is a highly effective disintegrant, meaning it helps tablets and capsules break apart into smaller particles in the body, allowing for faster drug release.
Oral Formulations:
It’s used in various oral drug delivery systems, including direct compression and granulation processes.
Enhances Bioavailability:
By promoting rapid disintegration, it helps improve the bioavailability of active pharmaceutical ingredients.

2. Other Applications:
Textile and Paper Industry: It can be used as a thickener and stabilizer in these industries.
Insecticide: It can be found in some insecticide formulations.
Oil-Well Drilling: It can be used to modify the properties of drilling fluids.

Packaging and Shipping

200KG/Bag

CROSCARMELLOSE SODIUM Storage

Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Containers that are opened must be carefully resealed and kept upright to prevent leakage.

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