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Alpha-Dihydroartemisinin CAS 81496-81-3

Assay: ≥98% 

Appearance: White crystalline powder

Packaging: 25kg/drum, 1kg/bag (Customizable)

Sample: Available

Description

Alpha-Dihydroartemisinin Quick Details

Chemical Name: Alpha-Dihydroartemisinin

Cas No.: 81496-81-3

Molecular Fomula: C15H24O5

Molecular Weight: 284.35

Appearance: White To Off-White Solid

Assay:≥98%

Alpha-Dihydroartemisinin Typical Properties

Items Specification
Appearance White To Off-White Solid
Purity ≥98%

Product Introduction:

Alpha-Dihydroartemisinin, commonly known as Dihydroartemisinin (DHA), is the active metabolite of artemisinin and a key semisynthetic derivative. It is formed by the reduction of artemisinin and features the same crucial peroxide bridge responsible for its antimalarial activity. It typically appears as a white crystalline powder.

DHA is considered one of the most potent and rapidly acting antimalarial drugs, often used in Artemisinin-based Combination Therapies (ACTs) due to its high efficacy and good tolerability.

Main Uses:

  1. Antimalarial Drug (Active Pharmaceutical Ingredient – API): Dihydroartemisinin is a primary active pharmaceutical ingredient used in the formulation of antimalarial drugs, particularly in highly effective Artemisinin-based Combination Therapies (ACTs). It is active against all species of malaria parasites, including multidrug-resistant Plasmodium falciparum.

  2. Pharmaceutical Intermediates: DHA itself serves as a crucial intermediate for the synthesis of other important artemisinin derivatives, such as artemether and artesunate, which are also widely used in ACTs.

  3. Research and Development: Beyond malaria, Dihydroartemisinin is a subject of ongoing research for its potential therapeutic applications. Studies explore its activity against various cancers, parasitic infections (e.g., schistosomiasis), and some autoimmune conditions.

  4. Combination Therapies: DHA is a preferred component in ACTs due to its rapid action and potent effect, often combined with a longer-acting partner drug to achieve high cure rates and prevent the development of drug resistance.

Alpha-Dihydroartemisinin Packaging And Shipping 

25Kg/Drum

Alpha-Dihydroartemisinin Storage

It Should Be Stored In a Clean, Dry And Cool Place, Preventing From Sunlight, Rain.

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