6-carboxyhexyl triphenylphosphonium bromide Quick Details

Chemical Name: 6-carboxyhexyl triphenylphosphonium bromide

CAS No.: 50889-30-0

Molecular Fomula: C25H28BrO2P

Molecular weight: 471.366381

Appearance: White to off-white powder

Assay：≥98%

6-carboxyhexyl triphenylphosphonium bromide application

Mitochondrial Targeting in Drug Delivery: Utilized as a TPP+ conjugate for selective mitochondrial accumulation in therapeutic agents, enhancing treatment of mitochondrial dysfunction, cancer, and oxidative stress-related diseases.
Intermediate in Wittig Reactions for Organic Synthesis: Serves as a phosphonium salt to generate ylides for stereoselective alkene formation, commonly in the synthesis of natural products like capsaicin or lipid analogs.
Anticancer Agent Conjugation: Incorporated into drug conjugates (e.g., with azithromycin or chitosan nanoparticles) to improve selectivity and efficacy against hepatic or other cancers via mitochondrial disruption.
Antimicrobial Compound Development: Used in synthesizing TPP+-linked phytochemicals or ionic liquids with enhanced antimicrobial activity against bacteria and fungi.
Antioxidant and Ligand Synthesis: Employed in creating cationic TPP+ derivatives as antioxidants or histamine H3 receptor ligands for potential neuroprotective or therapeutic applications.
Membrane Permeation and Ion Transport Studies: Leverages its lipophilic cation nature to facilitate ion transport across biological membranes, aiding research in cellular bioenergetics and drug permeation.
General Research Intermediate: Applied as a versatile building block in laboratory organic chemistry for alkylation, coupling, or functionalization in fine chemical and pharmaceutical intermediate production.

6-carboxyhexyl triphenylphosphonium bromide Packaging and Shipping

25kg/drum, Customized according to customer needs.

6-carboxyhexyl triphenylphosphonium bromide Storage

Ensure the room is cool, dry, dark and well ventilated.

6-carboxyhexyl triphenylphosphonium bromide CAS 50889-30-0