Description

2-Tetrahydrofuroic acid Details

Chemical Name: 2-Tetrahydrofuroic acid

Synonyms: Tetrahydro-2-furoic Acid; T2F; THFC; THFAC

CAS No.: 16874-33-2

Molecular Formula: C5H8O3

Molecular Weight: 116.12

Molecular Structure:

Appearance: Colorless to light yellow liquidAssay: 99%

Typical Properties

Melting point	21°C
Boiling point	128-129°C13 mm Hg(lit.)
Density	1.209g/mL at 25 °C(lit.)
Water Solubility	soluble
Appearance	Liquid
Colour	Transparent yellow to brown
Refractive index	n20/D 1.46 (lit.)

2-Tetrahydrofuroic acid Usage

2-Tetrahydrofuran-2-carboxylicacid (2-THFA) can be split into (R)-2-THFA and (S)-2-THFA. Chiral 2-tetrahydrofurancarboxylicacid is an important ligand synthon in asymmetric synthesis reactions. Among them, (R)-2-THFA is an important intermediate for the synthesis of the antibiotic furopenem, which can be used as an antagonist of the antigen VLA-4, and is also a chiral resolution agent for an important intermediate of the super flu drug Xofluza; (S)-2-THFA is the main raw material for the preparation of the chiral auxiliary (S)-acetyltetrahydrofuran, a raw material for the preparation of cephalosporin antibiotic intermediates, and an important intermediate for the preparation of the hormone LHRH that stimulates hormone release.

Packaging and Shipping

200kg/drum

2-Tetrahydrofuroic acid Storage

It should be stored in a clean, dry and cool place, preventing from sunlight, rain.

2-Tetrahydrofuroic Acid CAS 16874-33-2

Description

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