2-Methylimidazole CAS 693-98-1

2-Methylimidazole Quick Details

Chemical Name: 2-Methylimidazole

Synonyms: 2-MI; 2-Methyl-1H-imidazole

CAS No.: 693-98-1

Molecular Formula: C4H6N2

Chemical Structure:

Molecular weight: 82.1

Appearance: White crystal powder

Assay: 99%min

Typical Properties

2-methylimidazole synthesis method

1. Dehydrogenation by elimination of 2-methylimidazoline. 2-Methylimidazoline was heated and melted (melting point 107 ° C), active nickel was carefully added, and the temperature was raised to 200-210 ° C for 2 h. The temperature is lowered to below 150 ° C, dissolved in water, hot-pressed, and the active nickel is separated. The filtrate is concentrated to a temperature above 140 ° C, and the material is cooled to obtain 2-methylimidazole. The method is used to produce a product with a purity of ≥98%, and the 1t product consumes 1095 kg of ethylenediamine (95%) and 975 kg of acetonitrile. A preferred method is to use glyoxal and aldehyde as starting materials.

2. The 2-methylimidazoline was heated and melted (melting point 107 ° C), the active nickel was carefully added, the temperature was raised to 200-210 ° C, and the catalytic dehydrogenation reaction was carried out for 2 h. The temperature is lowered to below 150 ° C, dissolved in water, hot-pressed, and the active nickel is separated. The filtrate is concentrated to a temperature above 140 ° C, and the material is cooled to obtain 2-methylimidazole. 3. The glyoxal method is based on glyoxal as a raw material, and is subjected to a cyclization reaction with acetaldehyde and ammonia at about 45 ° C, followed by dehydration and crystallization separation to obtain 2-methylimidazole. The advantages of the glyoxal process route are mainly due to the wide source of raw materials, short process route, low production cost and low pollution, so the process has a relatively strong advantage. Manufacturers of 2-methylimidazole in the country have adopted this process route.

2-Methylimidazole Application

High-efficiency curing agent and accelerator for epoxy resins (critical industrial application): It is a classic imidazole-based curing agent and accelerator for epoxy resin systems.

• Curing agent/accelerator: It can function independently as a medium-temperature curing agent for epoxy resins or as a high-efficiency accelerator for anhydride and dicyandiamide curing systems. It significantly lowers curing temperatures and shortens curing times while enhancing the heat resistance (raising the glass transition temperature, Tg), mechanical strength, and electrical insulation properties of the cured product.
• Application scenarios: Widely used in epoxy electronic potting compounds, copper-clad laminates (CCL), powder coatings, epoxy adhesives, and composite materials (such as wind turbine blades and carbon fiber pultruded parts).

Pharmaceutical intermediate: A key raw material for synthesizing anti-amoebic and anti-anaerobic drugs. It also serves as an active pharmaceutical ingredient (API) for feed additives used as growth promoters.

Structural ligand for Metal-Organic Frameworks (MOFs / ZIF-8): In the field of advanced materials, it acts as the core organic ligand for synthesizing ZIF-8—a representative metal-organic framework—which is widely used in gas adsorption and separation, catalysis, and sustained-release drug delivery systems.

Other uses: Can be used as an auxiliary agent in textile dyeing processes and as an additive in foam production.

Packaging and Shipping

25kg/Drum

2-Methylimidazole Storage

Must be stored in a cool, dry, and well-ventilated dedicated chemical warehouse.

Keep away from heat sources and open flames; suggested storage temperatures should not exceed 30°C.

Keep containers hermetically sealed and sheltered from humidity.