Chemical Name: 2-Nitrobenzenesulfonyl chloride
CAS No.: 1694-92-4
EC No.: 216-907-1
Molecular Formula: C6H4ClNO4S
Molecular Weight: 221.62 g/mol
Appearance: Off-white to light yellow crystalline powder or mass
Assay: 98.0% min
2-Nitrobenzenesulfonyl Chloride CAS 1694-92-4
Description
2-Nitrobenzenesulfonyl chloride Quick Details
Chemical Name: 2-Nitrobenzenesulfonyl chloride
Synonyms: o-Nitrobenzenesulfonyl chloride; 2-(Chlorosulphonyl)nitrobenzene; 1-(Chlorosulfonyl)-2-nitrobenzene; 2-Nitrophenylsulfonyl chloride; 2-Nitribenzenenesulfonyl chloride
CAS No.: 1694-92-4
EC No.: 216-907-1
Molecular Formula: C6H4ClNO4S
Molecular Weight: 221.62 g/mol
Appearance: Off-white to light yellow crystalline powder or mass
Assay: 98.0% min
2-Nitrobenzenesulfonyl chloride Specification
| Item | Specifications |
| Melting point | -1°C |
| Boiling point | 155 °C |
| Density | 0.89 g/mL at 20 °C (lit.) |
| Water Solubility | 2μg/L at 20℃ |
| Appearance | Liquid |
| Colour | Colorless |
| Flash point | 165 °C |
| Refractive index | n20/D 1.44 |
2-Nitrobenzenesulfonyl chloride Applications
Used as a key activating and protecting reagent in organic synthesis, specifically for the protection of primary and secondary amines to form nosyl derivatives (Nosyl protection).
Serves as an essential intermediate in the pharmaceutical industry for synthesizing diverse active pharmaceutical ingredients (APIs)
Widely applied in the Fukuyama amine synthesis process, allowing selective mono-alkylation of primary amines under mild reaction conditions.
2-Nitrobenzenesulfonyl chloride Packaging & Shipping
Standard Packaging: 25 kg fiber drums lined with double-layer moisture-proof polyethylene bags.
Customizable Packaging: Laboratory and R&D packaging (25 g, 100 g, 500 g, 1 kg, 5 kg) in sealed plastic bottles or aluminum foil bags available upon request.
2-Nitrobenzenesulfonyl chloride Storage
Temperature: Store in a cool, dry place, ideally at 2-8 C for long-term storage stability.